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procedure proc loess with smoothing factor 0.25  (SAS institute)
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SAS institute procedure proc loess with smoothing factor 0.25
Mean <t>GIR</t> profiles (PPP for PD). Two profiles each receiving Biocon's Insulin‐70/30 and HUMULIN 70/30 were excluded from the PPP (n = 72) for PD based on C‐peptide exclusion rules and during the blinded database release meeting (because of extended gaps in continuous glucose monitoring), respectively. GIR, glucose infusion rates; PD, pharmacodynamics; PPP, per‐protocol population
Procedure Proc Loess With Smoothing Factor 0.25, supplied by SAS institute, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Mean GIR profiles (PPP for PD). Two profiles each receiving Biocon's Insulin‐70/30 and HUMULIN 70/30 were excluded from the PPP (n = 72) for PD based on C‐peptide exclusion rules and during the blinded database release meeting (because of extended gaps in continuous glucose monitoring), respectively. GIR, glucose infusion rates; PD, pharmacodynamics; PPP, per‐protocol population

Journal: Diabetes, Obesity & Metabolism

Article Title: Pharmacokinetic and pharmacodynamic equivalence of Biocon's biosimilar Insulin 70/30 with US ‐licensed HUMULIN® 70/30 formulation in healthy subjects: Results from the RHINE ‐3 ( R ecombinant H uman IN sulin E quivalence‐3) study

doi: 10.1111/dom.14768

Figure Lengend Snippet: Mean GIR profiles (PPP for PD). Two profiles each receiving Biocon's Insulin‐70/30 and HUMULIN 70/30 were excluded from the PPP (n = 72) for PD based on C‐peptide exclusion rules and during the blinded database release meeting (because of extended gaps in continuous glucose monitoring), respectively. GIR, glucose infusion rates; PD, pharmacodynamics; PPP, per‐protocol population

Article Snippet: GIR max and other time‐related PD parameters were calculated from smoothed GIR profiles (SAS procedure PROC LOESS with smoothing factor 0.25).

Techniques: Drug discovery